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產(chǎn)品中心抗體/抗原標(biāo)簽/內(nèi)參抗體S0B0535SQSTM1/p62 Recombinant Rabbit mAb (S-R346)
產(chǎn)品型號：S0B0535
更新時間：2025-10-07
廠商性質(zhì)：生產(chǎn)廠家
訪問量：143
服務(wù)熱線15855403091
產(chǎn)品分類
Sequestosome-1 is a protein that in humans is encoded by the SQSTM1 gene. Also known as the ubiquitin-binding protein p62, it is an autophagosome cargo protein that targets other proteins that bind to it for selective autophagy. By interacting with GATA4 and targeting it for degradation, it can inhibit GATA-4 associated senescence and senescence-associated secretory phenotype. Mutations in SQSTM1 are a common cause of Paget's disease of bone.
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