Biotin Mouse Anti-Human CD16 Antibody (S-R440)

產(chǎn)品型號：S0B1822

更新時間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

訪問量：77

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

CD16, also known as FcγRIII, is a low-affinity IgG receptor expressed on various immune cells, including natural killer （NK） cells, monocytes, macrophages, and neutrophils. As a member of the immunoglobulin superfamily, CD16 plays a crucial role in immune responses by binding to the Fc portion of IgG antibodies. This interaction triggers several important immune functions such as phagocytosis, respiratory burst, and antibody-dependent cellular cytotoxicity （ADCC）, which are vital for defending against pathogens and cancer cells. CD16 exists in two forms, CD16a and CD16b, with CD16a being predominantly found on NK cells and monocytes, while CD16b is primarily expressed on neutrophils. Its ability to activate NK cells and enhance their cytotoxicity against target cells makes CD16 a significant target in cancer immunotherapy and antibody drug development.

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