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產(chǎn)品中心抗體/抗原流式抗體S0B5044Rat Anti-Mouse CD185 Antibody (S-R600)
產(chǎn)品型號：S0B5044
更新時間：2025-10-08
廠商性質(zhì)：生產(chǎn)廠家
訪問量：105
服務熱線15855403091
產(chǎn)品分類
CD185, also known as CXCR5 （C-X-C motif chemokine receptor 5）, is a seven-transmembrane G protein-coupled receptor primarily expressed on mature B cells, follicular helper T cells （Tfh）, and certain memory T cell subsets. It is essential for lymphocyte trafficking, particularly in directing T cells to B cell follicles within germinal centers in response to its ligand, CXCL13. CD185 plays a critical role in B cell maturation and the formation of high-affinity antibodies by facilitating interactions between Tfh cells and B cells. Additionally, it is involved in the regulation of neural stem cells and neuronal regeneration.
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