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S0B5128Pacific Blue Mouse Anti-Rat CD11b/c Antibody (S-R630)

產(chǎn)品型號(hào):S0B5128
更新時(shí)間:2025-10-08
廠商性質(zhì):生產(chǎn)廠家
訪問量:106
服務(wù)熱線15855403091
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CD11b and CD11c are integral components of the integrin family, which are heterodimeric transmembrane glycoproteins involved in cell adhesion and immune responses. CD11b, also known as integrin alpha M (ITGAM) or Mac-1, pairs with CD18 to form complement receptor 3 (CR3), playing a crucial role in mediating the uptake of complement-coated particles and pathogens. It is expressed on various immune cells, including macrophages, monocytes, granulocytes, and NK cells. Similarly, CD11c, also called integrin alpha X (ITGAX), forms complement receptor 4 (CR4) with CD18 and is involved in similar adhesive interactions and phagocytosis. Both CD11b and CD11c are commonly used as markers for immune cells, with CD11b/c antibodies often employed in research to identify microglia in the brain and other immune cells.
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