Rat Anti-Mouse CD71 Antibody (S-R684)

產(chǎn)品型號：S0B5177

更新時間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

CD71, also known as the transferrin receptor 1 （TfR1）, is a type II transmembrane glycoprotein that plays a crucial role in cellular iron uptake by binding to transferrin, which facilitates iron transport into the cell. This receptor is highly expressed on rapidly proliferating cells, including erythroid precursors, activated immune cells, and cancer cells, as these cells require significant iron for DNA synthesis and metabolic processes. In clinical contexts, CD71 is used as a marker for identifying immature red blood cells （such as proerythroblasts and reticulocytes） and is also associated with aggressive tumor growth in various cancers, including pancreatic and colon cancers. Additionally, studies have shown that CD71 expression on neutrophils can be linked to poor prognosis in pancreatic ductal adenocarcinoma （PDAC） patients, indicating its potential as a prognostic biomarker.

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