Alexa Fluor? 488 Rat Anti-Mouse CD140a Antibody (S-R682)

產(chǎn)品型號：S0B5317

更新時間：2025-10-08

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

CD140a, also known as Platelet-Derived Growth Factor Receptor Alpha （PDGFRα）, is a cell surface receptor tyrosine kinase that plays a crucial role in various biological processes. It is a member of the receptor tyrosine kinase （RTK） III class and is widely expressed in cells of mesenchymal origin, including fibroblasts, endothelial cells, glial cells, and certain tumor cells. CD140a binds to various isoforms of platelet-derived growth factors （PDGFs） such as PDGF-AA, PDGF-AB, and PDGF-BB, forming homodimers or heterodimers with CD140b （PDGFRβ） to mediate cellular responses. This receptor is involved in cell proliferation, differentiation, migration, and survival, and is essential for embryonic development, wound healing, and the regulation of platelet activation.

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