Armenian hamster Anti-Mouse CD272 Antibody (S-R709)

產(chǎn)品型號：S0B5425

更新時間：2025-10-09

廠商性質(zhì)：生產(chǎn)廠家

訪問量：108

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抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

CD272, also known as BTLA （B- and T-lymphocyte attenuator）, is an inhibitory receptor belonging to the CD28 immunoglobulin superfamily. It is a type I transmembrane glycoprotein expressed by most lymphocytes, including T and B cells. BTLA shares structural and functional similarities with CTLA-4 and PD-1, but it is distinct in that it interacts with the tumor necrosis factor receptor superfamily member 14 （TNFRSF14）, also known as herpesvirus entry mediator （HVEM）, rather than just the B7 family of cell surface receptors. This interaction plays a crucial role in negatively regulating T-cell immune responses. BTLA is involved in maintaining lymphocyte homeostasis and preventing excessive immune activation. It has potential implications in various diseases, including cancer and autoimmune disorders, where immune regulation is critical.

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