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產(chǎn)品中心抗體/抗原病理/IHC抗體S0B2108Wilms Tumor Protein (WT1) Recombinant Rabbit mAb (SDT-2864)
產(chǎn)品型號(hào)：S0B2108
更新時(shí)間：2025-10-09
廠商性質(zhì)：生產(chǎn)廠家
訪問(wèn)量：119
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Wilms tumor 1 （WT1） gene encodes a zinc finger transcription factor （WT1） that regulates genes involved in proliferation, differentiation and apoptosis, while it plays a central role in the embryogenesis of many tissues including the urogenital system, heart, and central nervous system.Although predominantly expressed in nucleus in normal cells, WT1 shuttles between the nuclear and cytoplasmic compartments. WT1 is detected in functional polysomes; interacts with the splice factor U2AF65; and is associated with nuclear mRNP particles in fetal kidney cells. In WT1‐expressing tumors, WT1 is mostly expressed in the cytoplasm and interacts with the actin cytoskeleton.
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