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產(chǎn)品中心抗體/抗原病理/IHC抗體S0B2166FAP Recombinant Rabbit mAb (SDT-R132)
產(chǎn)品型號(hào)：S0B2166
更新時(shí)間：2025-10-09
廠商性質(zhì)：生產(chǎn)廠家
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Fibroblast activation protein （FAP） is best known for its heightened expression in tumour stroma. This atypical serine protease has both dipeptidyl peptidase and endopeptidase activities, cleaving substrates at a post-proline bond. FAP expression is difficult to detect in non-diseased adult organs, but is greatly upregulated in sites of tissue remodelling, which include liver fibrosis, lung fibrosis, atherosclerosis, arthritis, tumours and embryonic tissues. Due to its restricted expression pattern and dual enzymatic activities, FAP is emerging as a unique therapeutic target [PMID: 24470260].
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